Theories of Everything with Curt Jaimungal

• Hacking Life's Code: The Future of Bioelectric Medicine | Michael Levin

  Dr. Michael Levin is on the verge of revolutionizing medicine by unlocking the bioelectric code that governs how cells communicate, heal, and build complex structures. His work reveals that intelligence exists at every level of biology—allowing us to reprogram tissues, regenerate limbs, and even suppress cancer by restoring cellular memory and connection. As a listener of TOE you can get a special 20% off discount to The Economist and all it has to offer! Visit https://www.economist.com/toe Join My New Substack (Personal Writings): https://curtjaimungal.substack.com Listen on Spotify: https://tinyurl.com/SpotifyTOE Become a YouTube Member (Early Access Videos): https://www.youtube.com/channel/UCdWIQh9DGG6uhJk8eyIFl1w/join Links: - Michael Levin on TOE: https://www.youtube.com/watch?v=c8iFtaltX-s - The Levin Lab (website): https://drmichaellevin.org/ - Michael’s blog: https://thoughtforms.life/ - Michael’s presentations: https://drmichaellevin.org/presentations/ - Michael and colleagues discussing anthrobots and other groundbreaking research on TOE: https://www.youtube.com/watch?v=hG6GIzNM0aM - ekkólapto (website): https://www.ekkolapto.org/ - ekkólapto Events: https://lu.ma/calendar/cal-GqNtzHBC2j8ARjb - Curt Jaimungal’s presentation at Polymath: https://www.youtube.com/watch?v=YCkMyjzQDeg - Will Hahn on TOE: https://www.youtube.com/watch?v=xr4R7eh5f_M Timestamps: 00:00 Introduction 02:45 The Role of Bioelectricity in Medicine 7:00 Multi-Scale Problem Solving 7:55 The Intelligence of Development 11:41 Decoding Electrical Memories 12:29 The Power of Bioelectric Signals 13:20 Rewiring Cellular Communication 15:29 Cancer and Cellular Networks 16:30 Birth Defects and Bioelectricity 18:28 Regeneration and Bioelectric Pathways 22:50 Inducing Novel Organs 25:35 The Future of Medicine 26:24 Audience Interaction and Questions 31:34 The Future of Bioelectricity 38:55 Integrating Bioelectricity with Evolution 44:17 Preventative Strategies in Medicine 45:45 Closing Remarks and Resources 46:30 Conclusion Support TOE on Patreon: https://patreon.com/curtjaimungal Twitter: https://twitter.com/TOEwithCurt Discord Invite: https://discord.com/invite/kBcnfNVwqs #science #biology Learn more about your ad choices. Visit megaphone.fm/adchoices

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  50:27
• The Emergence of the Super Point from Nothing

  I'm back, baby. I've been away traveling for podcasts and am excited to bring you new ones with Michael Levin, William Hahn, Robin Hanson, and Emily Riehl, coming up shortly. They're already recorded. I've been recovering from a terrible flu but pushed through it to bring you today's episode with Urs Schreiber. This one is quite mind-blowing. It's quite hairy mathematics, something called higher category theory, and how using this math (which examines the structure of structure) allows one manner of finding "something" from "nothing." Here, "nothing" means the empty set, and "something" is defined as fermions and even 11D supergravity. It's the first time this material has been presented in this manner. Enjoy. NOTE: Link to technical details are here from Urs Schreiber: https://ncatlab.org/schreiber/show/Peri+Pantheorias As a listener of TOE you can get a special 20% off discount to The Economist and all it has to offer! Visit https://www.economist.com/toe Join My New Substack (Personal Writings): https://curtjaimungal.substack.com Listen on Spotify: https://tinyurl.com/SpotifyTOE Become a YouTube Member (Early Access Videos): https://www.youtube.com/channel/UCdWIQh9DGG6uhJk8eyIFl1w/join Links Mentioned: - nLab website: https://ncatlab.org/nlab/show/HomePage - Paper on category theory: https://people.math.osu.edu/cogdell.1/6112-Eilenberg&MacLane-www.pdf - “Higher Topos Theory for Physics” (Urs’s talk): https://www.youtube.com/watch?v=GD20W6vxMI4 - “Higher Topos Theory for Physics” (Urs’s paper): https://arxiv.org/pdf/2311.11026 - Stephen Wolfram on TOE: https://www.youtube.com/watch?v=0YRlQQw0d-4 - Feynman’s thesis: https://faculty.washington.edu/seattle/physics541/2012-path-integrals/thesis.pdf - Differential cohomology in a cohesive ∞-topos (Urs’s paper): https://arxiv.org/pdf/1310.7930 - M-Theory from the Superpoint (paper): https://arxiv.org/pdf/1702.01774 - Character Map in Non-Abelian Cohomology, The: Twisted, Differential, and Generalized (textbook): https://amzn.to/4bFuz7H - TOE’s String Theory Iceberg: https://www.youtube.com/watch?v=X4PdPnQuwjY Timestamps: 00:00 Introduction 01:27 The Creation of nLab 04:36 Philosophy Meets Physics 07:55 The Role of Mathematical Language 09:32 Emergence from Nothing 16:25 Towards a Theory of Everything 22:21 The Problem with Modern Physics 25:31 Diving into Category Theory 35:30 Understanding Adjunctions 41:46 The Significance of Duality 52:54 Exploring Toposes 1:14:20 The UNEDA Lemma and Generalized Spaces 1:16:37 Charts in Physics 1:20:55 Introduction to Infinitesimal Disks 1:23:56 The Emergence of Supergeometry 1:27:33 Transitioning to Gauge Theories 1:28:11 Exploring Singularities in Physics 1:32:50 The Role of Superformal Spaces 1:36:44 Functors and Their Implications 1:40:51 From Nothing to Emergent Structures 1:43:04 Hegel's Influence on Modern Physics 1:54:07 Discovering Higher-Dimensional Structures 1:56:30 The Path to 11-Dimensional Supergravity 1:57:21 Universal Central Extensions 2:03:21 The Journey to M-Theory 2:11:19 Globalizing the Structure of Supergravity 2:15:36 Understanding Global Charges in Physics 2:23:31 Dirac's Insights into Gauge Potentials 2:30:21 The Quest for Non-Perturbative Physics 2:39:04 Conclusion Support TOE on Patreon: https://patreon.com/curtjaimungal Twitter: https://twitter.com/TOEwithCurt Discord Invite: https://discord.com/invite/kBcnfNVwqs #science #theoreticalphysics Learn more about your ad choices. Visit megaphone.fm/adchoices

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  2:50:39
• Harvard Scientist Rewrites the Rules of Quantum Mechanics | Scott Aaronson Λ Jacob Barandes

  Join Curt Jaimungal as he welcomes Harvard physicist Jacob Barandes, who claims quantum mechanics can be reformulated without wave functions, alongside computer scientist Scott Aaronson. Barandes’ “indivisible” approach challenges the standard Schrödinger model, and Aaronson offers a healthy dose of skepticism in today's theolocution. Are we on the cusp of a radical rewrite of reality—or just rebranding the same quantum puzzles? As a listener of TOE you can get a special 20% off discount to The Economist and all it has to offer! Visit https://www.economist.com/toe Join My New Substack (Personal Writings): https://curtjaimungal.substack.com Listen on Spotify: https://tinyurl.com/SpotifyTOE Become a YouTube Member (Early Access Videos): https://www.youtube.com/channel/UCdWIQh9DGG6uhJk8eyIFl1w/join Timestamps: 00:00 Introduction to Quantum Mechanics 05:40 The Power of Quantum Computing 36:17 The Many Worlds Debate 1:09:05 Evaluating Jacob's Theory 1:13:49 Criteria for Theoretical Frameworks 1:17:15 Bohmian Mechanics and Stochastic Dynamics 1:18:51 Generalizing Quantum Theory 1:22:32 The Role of Unobservables 1:31:08 The Problem of Trajectories 1:39:39 Exploring Alternative Theories 1:50:29 The Stone Soup Analogy 1:56:20 The Limits of Quantum Mechanics 2:01:57 The Nature of Laws in Physics 2:14:57 The Many Worlds Interpretation 2:22:40 The Search for New Connections Links Mentioned: - Quantum theory, the Church–Turing principle and the universal quantum computer (article): https://www.cs.princeton.edu/courses/archive/fall04/cos576/papers/deutsch85.pdf - The Emergent Multiverse (book): https://amzn.to/3QJleSu Jacob Barandes on TOE (Part 1): https://www.youtube.com/watch?v=7oWip00iXbo&t=1s&ab_channel=CurtJaimungal - Scott Aaronson on TOE: https://www.youtube.com/watch?v=1ZpGCQoL2Rk - Quantum Theory From Five Reasonable Axioms (paper): https://arxiv.org/pdf/quant-ph/0101012 - Quantum stochastic processes and quantum non-Markovian phenomena (paper): https://arxiv.org/pdf/2012.01894 - Jacob’s “Wigner’s Friend” flowchart: https://shared.jacobbarandes.com/images/wigners-friend-flow-chart-2025 - Is Quantum Mechanics An Island In Theory Space? (paper): https://www.scottaaronson.com/papers/island.pdf - Aspects of Objectivity in Quantum Mechanics (paper): https://philsci-archive.pitt.edu/223/1/Objectivity.pdf - Quantum Computing Since Democritus (book): https://amzn.to/4bqVeoD - The Ghost in the Quantum Turing Machine (paper): https://arxiv.org/pdf/1306.0159 - Quantum mechanics and reality (article): https://pubs.aip.org/physicstoday/article/23/9/30/427387/Quantum-mechanics-and-realityCould-the-solution-to - Stone Soup (book): https://amzn.to/4kgPamN - TOE’s String Theory Iceberg: https://www.youtube.com/watch?v=X4PdPnQuwjY - TOE’s Mindfest playlist: https://www.youtube.com/playlist?list=PLZ7ikzmc6zlOPw7Hqkc6-MXEMBy0fnZcb Support TOE on Patreon: https://patreon.com/curtjaimungal Twitter: https://twitter.com/TOEwithCurt Discord Invite: https://discord.com/invite/kBcnfNVwqs #science #theoreticalphysics Learn more about your ad choices. Visit megaphone.fm/adchoices

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  2:42:14
• The Science of New States of Consciousness | Andrés Gómez Emilsson

  Andrés Gómez Emilsson, director of the Qualia Research Institute and a pioneering researcher in the mathematical study of consciousness, explores the nature of awareness from both philosophical and scientific angles. He recounts his journey that led to founding the Qualia Research Institute—aimed at reducing suffering and enhancing experience. He discusses the transformative potential of psychedelics, the view of the self as a series of experiences, and how sensory resonance ("impedance matching") shapes our awareness. As a listener of TOE you can get a special 20% off discount to The Economist and all it has to offer! Visit https://www.economist.com/toe Join My New Substack (Personal Writings): https://curtjaimungal.substack.com Listen on Spotify: https://tinyurl.com/SpotifyTOE Become a YouTube Member (Early Access Videos): https://www.youtube.com/channel/UCdWIQh9DGG6uhJk8eyIFl1w/join Timestamps: 00:00 The Most Important Problem 01:49 The Hard Problem and Ontologies 05:15 Journey into Consciousness 09:06 The Qualia Research Institute 10:49 Shattering Realities 17:12 Happiness vs. Meaning 19:15 Defining Happiness 25:28 Psychological Egoism 33:45 Understanding Consciousness 38:01 The Qualia Research Institute's Goals 49:21 Exploring Impedance Matching 58:25 The Dance of Dissonance 1:03:22 The Nature of Suffering 1:10:32 The Concept of Oneness 1:17:02 Zero Ontology Explained 1:27:20 The Nature of Reality 1:28:57 The Self and Sense of Self 1:30:53 Stages of Consciousness 1:37:35 Transformations in Consciousness 1:46:20 The Role of Psychedelics 2:02:01 Exploring 5-MeO-DMT 2:21:03 Psychedelics and Buddhist Philosophy 2:45:32 Insights on Jhana States 2:51:31 Conclusion and Reflections Links Mentioned: - Qualia Research Institute (website): https://qri.org/ - Andres’s Qualia profile: https://qri.org/people/andr%C3%A9s-g%C3%B3mez-emilsson - David Chalmers’s 2024 presentation at Mindfest: https://www.youtube.com/watch?v=5r9V1ryksnw - Bernardo Kastrup on TOE: https://www.youtube.com/watch?v=lAB21FAXCDE - The Hedonistic Imperative (book): https://amzn.to/3Di7Xx5 - Why Does Anything Exist? (book): https://www.amazon.com/Why-Does-Anything-Exist-Mysteries-ebook/dp/B0DKBHMC3C - Mastering the Core Teachings of the Buddha (book): https://www.amazon.com/Mastering-Core-Teachings-Buddha-Unusually/dp/1911597108 - Andres on The DemystifySci Podcast: https://www.youtube.com/watch?v=jjWDURKNe2Q - ‘Replications’ group on Reddit: https://www.reddit.com/r/replications/ - Stuart Hameroff’s Mindfest presentation: https://www.youtube.com/watch?v=0_bQwdJir1o - The Doors of Perception (book): https://amzn.to/4ijduTb - From Neural Activity to Field Topology (article): https://qualiacomputing.com/2025/02/09/from-neural-activity-to-field-topology-how-coupling-kernels-shape-consciousness/ - Seeing That Frees (book): https://amzn.to/43fm15m - Practicing the Jhanas (meditation series): https://www.youtube.com/playlist?list=PLO6hhaAzLmiqUzBYuLLJQ8FexOTRxz8xF - The Dalai Lama, Psychedelics & Cher (article): https://tricycle.org/article/dalai-lama-psychedelics-cher/ - Advice to Sigālaka (article): https://suttacentral.net/dn31/en/sujato?lang=en&layout=plain&reference=none¬es=asterisk&highlight=false&script=latin Support TOE on Patreon: https://patreon.com/curtjaimungal Twitter: https://twitter.com/TOEwithCurt Discord Invite: https://discord.com/invite/kBcnfNVwqs #science #consciousness #mind Learn more about your ad choices. Visit megaphone.fm/adchoices

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  2:56:01
• Academia's Darkest Secret: The Graduate Student Crisis... | Tyler Cowen

  In today's episode of Theories of Everything, Tyler Cowen proposes that tariffs erode economic efficiency, ultimately passing much of the burden onto smaller countries such as Canada. Moreover, he suggests that the rise of AI and evolving institutional structures demand both intellectual humility and stronger mentorship for a more resilient academic landscape. As a listener of TOE you can get a special 20% off discount to The Economist and all it has to offer! Visit https://www.economist.com/toe Join My New Substack (Personal Writings): https://curtjaimungal.substack.com Listen on Spotify: https://tinyurl.com/SpotifyTOE Become a YouTube Member (Early Access Videos): https://www.youtube.com/channel/UCdWIQh9DGG6uhJk8eyIFl1w/join Links Mentioned: - Tyler’s website: https://tylercowen.com/ - Tyler’s blog: https://marginalrevolution.com/ - Tyler’s podcast: https://conversationswithtyler.com/ - Talent: How to Identify Energizers, Creatives, and Winners Around the World (book): https://www.amazon.com/Talent-Identify-Energizers-Creatives-Winners/dp/1250275814 ---------------------- Timestamps: 00:00 - Tariffs and Trade Policies 01:21 Economic Consequences of Tariffs 03:07 Canada as a 51st State? 04:00 Canada's Defense Spending Debate 05:41 Positive Aspects of Hostility 06:35 Transitioning to Theoretical Economics 08:07 The Role of Tenure 11:43 The Academy's Strengths 13:04 Problems in Academia 14:08 Understanding the Grant System 15:10 The Need for Grants 16:33 Is the Academic System Broken? 17:18 Improving the Academic System 17:47 The Role of AI in Academia 22:39 Exploring Deep Research 29:32 Writing as Thinking 31:53 Truth in Worldviews 33:22 Patchwork Theory of Reality 34:11 Economics and Theories of Everything 35:07 Disagreements Among Intelligent People 37:48 The Concept of Metarationality 45:10 Cultivating Metarationality 46:55 Distinction Between Stamina and Grit 49:03 Risk-Taking in Academia 51:28 Interviewing Style 56:28 The Value of Preparation 1:13:33 Critiquing Nassim Taleb 1:18:23 Public Debates vs. Private Discussions 1:20:46 Focus on Money 1:22:45 Healthy vs. Unhealthy Ambition 1:23:49 Complexity in Theories of Everything 1:24:39 The Importance of Mentoring 1:26:08 Current Projects and Interests 1:31:15 Advice for Students 1:32:39 The Future of Networking 1:32:53 Closing Thoughts and Reflections -------------------- Support TOE on Patreon: https://patreon.com/curtjaimungal Twitter: https://twitter.com/TOEwithCurt Discord Invite: https://discord.com/invite/kBcnfNVwqs #economy #science #technology #news #tariffs Learn more about your ad choices. Visit megaphone.fm/adchoices

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  1:37:12

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