First Principles with Christian Keil

• Is It Possible to Build SAFE Nuclear Reactors? | Matt Loszak, Aalo Atomics

  Matt Loszak is building a nuclear reactor factory for a new kind of reactor: one that is almost impossible to melt down.

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• The World's Safest Humanoid Robots

  1X Technologies is building the world's safest autonomous, humanoid robots.And they want to start selling robots into consumer homes next year. How do you make a robot safe for humans? The answer is complicated — so I went to 1X HQ in Sunnyvale, CA to find out.

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• The World's Quietest Electric Engine | Ian Villa, Whisper Aero

  Engines are loud — Whisper Aero is changing that.

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• How To Build a 1-Terawatt, 600,000 Amp Pulsed Power Generator | JC Btaiche, Fuse Energy

  Season 2, Episode 1: JC Btaiche, Fuse Energy======Links:ElectroBOOM: https://www.youtube.com/watch?v=_PcBgym21TAFuse's Paper in Nature: https://www.nature.com/articles/s41598-024-67774-4Fuse — https://www.f.energyPeople:JC Btaiche — https://x.com/JCBtaiche10Christian Keil — https://x.com/pronounced_kyle

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• #15: The First Principles Approach to Not Dying | Bryan Johnson

  Today’s episode is brought to you by Strata. Modernize your IAM with Identity Orchestration. Visit https://strata.io/firstprinciples to learn more!======Episode 15: Bryan Johnson spends $2m/year to not die. But this is more than just a health craze — it’s the birth of a new, secular religious movement. Here’s what Bryan believes.======(00:00) - Introduction(01:13) - Zeroth Principles Thinking: Going Beyond First Principles(04:05) - The Journey to "Don't Die": Bryan's Thought Experiments and Realizations(07:28) - Is "Don't Die" a Religion? Examining the Parallels(10:40) - Bryan's Roles in "Don't Die": Philosopher, Embodiment, Message Bearer(13:05) - Sponsor Break(14:08) - Quantifying Death: Introducing "Die Scores" for Behaviors and Choices(17:03) - What is Death and What is Aging? A First Principles Perspective(19:40) - Measuring Biological Age: Organ by Organ Analysis of Bryan's Body(23:48) - The Penis as a Marker of Overall Health and Vitality(26:33) - Epigenetic Clocks and the Pace of Aging Calculated Tests(30:18) - Bryan's Experience with Follistatin Gene Therapy(32:25) - Kernel: Building a Mass Market Brain Interface with Time-Domain FNIRS(36:48) - The Power Law Interventions: Identifying the Most Effective Longevity Levers(39:22) - Assembling a Team of Scientific Misfits to Tackle Aging(41:05) - Dreaming Up Ideas: Bryan's Nocturnal Creativity(42:15) - Telomeres and the Risks of Telomerase Gene Therapy(44:38) - Reflections on the Challenges of Commercializing Deep Tech(46:29) - Conclusion: Banding Together to Build an Amazing Future======Links:Christian Keil – https://twitter.com/pronounced_kyleBryan Johnson - https://x.com/bryan_johnsonBryan Johnson Personal Website - https://www.bryanjohnson.com/Blueprint - https://blueprint.bryanjohnson.com/======Production and marketing by The Deep View (https://thedeepview.co). For inquiries about sponsoring the podcast, email [email protected]======Checkout the video version here → http://tinyurl.com/4fh497n9🔔 Follow to stay updated with new uploads

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